I create a new topic with my new problem :
After one day, i acheive to create a good .prf file for my outlook 2010 for disabling cache mode and .ost file .
I do that in my setup capture:
Delete the following registry key values:
HKEY_CURRENT_USER\Software\Microsoft\Office\11.0\Outlook\Setup\First-Run
HKEY_CURRENT_USER\Software\Microsoft\Office\11.0\Outlook\Setup\FirstRun
In the
HKEY_CURRENT_USER\Software\Microsoft\Office\11.0\Outlook\Setup subkey,
set the value of ImportPRF to a string value that specifies the name and
path of the PRF file. For example, set ImportPRF to *
server1\share\outlook.prf*.
It works. But I've got a little problem.
If I add a new mailbox in my outlook (generally i've got 2 mailbox : my
own mailbox and one of the support.) the mailbox I add doesn't take the
prf file, in fact outlook create a ost file with a local copy of
mymailbox which i doesn't want! 
I've got a second question because I don't find answer on the web.I'm going to migrate from office 2003 to this outlook 2010 virtualised with Thinapp and I don't know how to do with signatures? When I open outlook there is nothing...
If I create a signature it's in :c$\Documents and Settings\UserName\Application Data\Thinstall\Microsoft Office Professionnel Plus 2010\%AppData%\Microsoft\Signatures
If I copy old signature in this folder when I open Outlook it don't see it...!
If you have a little tip to help me it will be cool.